Chapter 1: Conceptualization First well-nigh history: Kraepelin is the central family in this chapter. Differentiated insane disease from dementia praecox (SCZ). merge melancholia (DEP) and circular psychoses (BPAD, SAFD) into one category. His first harmonic insight was that recurrence is key. Bleueler flocculent the singularity again, putting SCZ and BPAD on a spectrum. SCZ sx were key and affectional sx were non-specific. He set the tip for the unipolar-bipolar distinction. unipolar vs. Bipolar: G/J spend untold time arguing that unipolar-bipolar de printing pression is less helpful than the theme of recurrence. Heterogeneity: Unipolar distemper very heterogeneous group. So is bipolar. Early classification schemes (1) duty tour out different epidemiology mingled with MD, Md, dM and dm groups. effectuate: umteen studies show that unipolar:bipolar ~1:1. So what is the unipolar/bipolar distinction: Phenomenology of Depression| Bipolar| Unipolar| inhering Course| | | Age of fire| Young| Old| | press range| Wider range| # sequences| more than(prenominal)| brusque| Length possibility| piteouser| continuing| Cycle length| womb-to-tomb| shorter| Precipitant of episode| more than important at barrage| ?| Inter-episode mood lability| more(prenominal)| less(prenominal)| | | | marital Status| Not a RF| RF| | | | Epedimiology| | | support time risk| 1.

5%| 10-15%| sex activity| M=F| F>M| SA| more than| less(prenominal)| | | | genetic science| more hereditary| Less| | | | biologic| | | Pain aesthesia| Less| more than| Sleep duration| coarse| Short| Seasonal| D-fall/ wintertime M-spring/summer| D-spring| | | | Pharm| | | Response to AD| Less| to a greater extent| revive of response to AD| More| Less| Tolerance to ADs| More freq| Less freq| Switch w/ ADs| More| Less| warning(a) response to ADs| Less| More| around notes on aberration: 1) unipolar aberration is credibly idealistic (<10% of BPAD). 2) Primacy of mania (2): all depression follows exhilaration egress (mania, hypomania,...If you want to light a full essay, order it on our website:
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